Blood Sisters tells the story of two friends Sarah (Ini Dima-Okojie) and Kemi (Nancy Isime). Sarah is engaged to her dream man, Kola (Deyemi Okanlawon.) However, their seemingly idyllic union has a dark side.
Unlike most people, Melody cannot walk or talk, but she is smarter than most of the adults who try to diagnose her. Her classmates dismiss her as mentally challenged but Melody refuses to be defined by cerebral palsy.